Attention to detail is a stronger candidate endophenotype of AN compared to BN, where poor global integration may be more relevant. The combined effect of superior attention to detail and poor global integration ("weak coherence") was present in 42.3% of active cases and corresponded with a more severe illness, elevated obsessive-compulsive symptoms, and a higher likelihood of comorbid clinical anxiety and self-harm.
Those with BN and their unaffected sisters showed a profile more consistent with poor global integration. Superior attention to detail was found across all AN groups including recovered AN and unaffected AN sisters.
A total of 266 women (including AN, BN, recovered AN, unaffected sisters of AN/BN & control women) undertook a thorough clinical assessment and were administered two neuropsychological measures of attention to detail (Group Embedded Figure Test Rey-Osterrieth Complex Figure).
To investigate whether attention to detail is a similarly strong candidate endophenotype of anorexia (AN) and bulimia nervosa (BN), and to explore the incidence and clinical correlates of attention to detail.
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